MOVErs from DSEV
List of MOVE fellowship awardees (MOVErs)
Affiliation
Postdoc
Department of Animal and Veterinary Sciences
MOVE host lab
Prof. Alireza Fazeli and Dr. Suranga Kodithuwakku
University of Tartu, Institute of Biomedicine and Translational Medicine
Estonian University of Life Sciences, Institute of Veterinary Medicine and Animal Sciences
Estonia
Grant amount and period of the research stay
DKK 15.000 for 2 months (Oct 2025 – Nov 2025)
EV techniques
EV isolation, upscaling and characterization from parasite vesicles
Project title
EV isolation and upscaling from helminths, host-cells and host feces
Project in a nutshell
EVs from Ascaridia galli are considered promising vaccine candidates, but their development is currently constrained by insufficient characterization and limited large-scale production. In this project, deep characterization and upscaling of A. galli EV production are pursued using combined differential centrifugation and size exclusion chromatography to improve EV yield, purity, and biological integrity. Isolation of EVs from fecal samples is also addressed, building on protocols developed by the host group and enabling analysis of parasite- and host-derived EVs under natural infection conditions. Access to the advanced EV isolation expertise and standardized methodologies available in Tartu is therefore considered essential to overcome current bottlenecks, enable antigen discovery, and support future comparative EV analyses across parasites and host systems.
Affiliation
Postdoc
Department of Clinical Biochemistry
MOVE host lab
Dr. Julia Kuligowski
Senior Researcher
Health Research Institute La Fe
Spain
Grant amount and period of the research stay
DKK 15.000 for 1 month (Mar 2026 – Apr 2026)
EV techniques
Organ-specific EVs, EV biomarkers, Proteomics, Lipidomics, Obesity complications
Project title
Characterization of liver-derived extracellular vesicle cargo for biomarker discovery in obesity-related complications
Project in a nutshell
This project aims to identify minimally invasive biomarkers for metabolic dysfunction–associated steatotic liver disease (MASLD) using circulating extracellular vesicles (EVs) derived from the liver. By analyzing their molecular cargo, we seek to improve the detection, stratification, and monitoring of MASLD in individuals with obesity. The study integrates clinical data with advanced molecular profiling of EVs to better understand disease progression and response to weight-loss interventions. Ultimately, this work supports the development of liquid biopsy approaches for liver disease management.